Which type of lipoprotein is primarily formed from the remnants of chylomicrons?

The correct answer is that remnants of chylomicrons primarily give rise to intermediate-density lipoprotein (IDL). Chylomicrons are lipoproteins formed in the intestines that transport dietary lipids, primarily triglycerides, into the bloodstream. After chylomicrons have delivered their triglyceride content to peripheral tissues, they are transformed into chylomicron remnants. These remnants retain some triglycerides but also contain a significant amount of cholesterol and cholesterol esters.

These remnants are then taken up by the liver or converted into IDL. IDL itself can further be transformed into low-density lipoprotein (LDL) as it loses even more triglycerides. While very-low-density lipoprotein (VLDL) is involved in the transport of endogenous triglycerides and cholesterol synthesized by the liver, it is not the product of chylomicron remnants. High-density lipoprotein (HDL) is primarily involved in reverse cholesterol transport and does not arise from chylomicrons at any stage.

Understanding the pathway of lipoprotein metabolism highlights the significance of IDL in the lipid transport system following the activity of chylomicrons.