Harr Clinical Chemistry Practice Test

Question: 1 / 860

What is a true statement regarding urobilinogen?

It is formed in the intestines by bacterial reduction of bilirubin

The statement that urobilinogen is formed in the intestines by bacterial reduction of bilirubin is accurate. When bilirubin is produced from the breakdown of hemoglobin, it is transported to the liver, where it gets conjugated and then secreted into the bile. Once the bile reaches the intestines, intestinal bacteria metabolize the conjugated bilirubin to produce urobilinogen. This compound can be reabsorbed into the bloodstream, some of which is eventually excreted in urine, while the remaining is converted to stercobilin, giving feces their characteristic brown color. This process highlights the important role of gut bacteria in transforming bilirubin into urobilinogen, making the statement true.

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It consists of a single water-soluble bile pigment

It is measured by its reaction with p-aminosalicylate

In hemolytic anemia, it is decreased in urine and feces

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