Which form of jaundice occurs within days of delivery and is not due to normal neonatal hyperbilirubinemia?

Lucey-Driscoll syndrome is characterized by the onset of jaundice shortly after birth, typically within the first few days of delivery. This condition is specifically related to an immaturity in the liver's ability to process bilirubin, leading to an unconjugated hyperbilirubinemia. Unlike the normal neonatal hyperbilirubinemia that many newborns experience due to factors like the breakdown of fetal hemoglobin and immature liver function, Lucie-Driscoll syndrome is distinct because it is not simply a variant of this normal physiological process.

This condition may be confused with other syndromes, but it is essential to note that it usually resolves within a few weeks as the infant's liver matures. The other syndromes listed are typically not associated with early postnatal jaundice or may present differently; for instance, Gilbert syndrome tends to manifest later in life and is associated with benign unconjugated hyperbilirubinemia, while Rotor and Dubin-Johnson syndromes are more related to conjugated hyperbilirubinemia due to inherited defects in bilirubin transport. Thus, the identification of Lucey-Driscoll syndrome is key in understanding the specific nature of jaundice that arises shortly after delivery and differenti