Which factor can interfere with the measurement of LD?

The correct choice is the interference caused by slight hemolysis during sample collection. Lactate dehydrogenase (LD) is an enzyme found in many tissues, and its levels in the blood can be influenced by hemolysis. When red blood cells are damaged during the sample collection process, they release LD into the plasma, potentially leading to falsely elevated levels of the enzyme in the assay. This means that any degree of hemolysis can compromise the integrity of the sample, creating misleading results, which is why it is a significant factor to consider in the measurement of LD.

Hemolysis can introduce variability and can be a common issue during blood sample collection procedures, reinforcing the importance of handling and processing blood samples carefully to avoid altering the biochemical measurements intended for analysis. Other factors such as storage conditions may influence enzyme stability, but slight hemolysis is specifically known to affect LD measurements directly by changing the enzyme concentration in the sample.