Which enzyme is usually decreased in liver disease?

In liver disease, Pseudocholinesterase levels are typically decreased due to the liver's diminished ability to synthesize proteins. Pseudocholinesterase is an enzyme produced primarily by the liver, and its concentration can serve as an indicator of hepatic synthetic function. When liver function is compromised, the production of this enzyme decreases, leading to lower serum levels.

The measurement of Pseudocholinesterase can help in assessing liver health due to its reliance on liver function for synthesis. In contrast, the other enzymes mentioned do not exhibit a consistent correlation with liver disease to the same extent. For example, while other enzymes may be involved in various metabolic processes, they either do not reflect liver function directly or they can be influenced by other factors, making them less reliable indicators specifically for liver disease.