Which electrochemical method can also be utilized to measure glucose in plasma alongside polarography?

Study for the Harr Clinical Chemistry Test. Use flashcards and multiple choice questions for each topic covered. Each question includes hints and explanations to help you understand. Prepare effectively for success!

Amperometry is a valid electrochemical method for measuring glucose levels in plasma, as it involves measuring the current that flows in response to a potential applied to an electrode in the presence of glucose. This technique is particularly useful because it allows for the detection of glucose through the oxidation reactions that occur at the electrode surface. When glucose is oxidized, it generates electrons, resulting in a measurable current. This current is directly proportional to the concentration of glucose in the sample, making it an effective method for quantifying glucose levels.

Amperometry is advantageous for clinical applications because it can provide real-time measurements and a high level of specificity for glucose, particularly when used with specific glucose oxidase enzymes that enhance sensitivity and selectivity. This method is often used in glucose meters and continuous glucose monitoring systems, highlighting its practical application in medical settings.

In contrast, while the other methods listed can also provide valuable analytical information, they do not typically apply in the same direct manner for glucose measurement as amperometry. For example, polarography focuses on measuring current as it varies with potential in a solution, typically used for other types of analytes. Thus, amperometry stands out as a direct and effective approach alongside polarography for glucose quantification in plasma.

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