Which abnormal laboratory result is typically found in von Gierke's disease?

In von Gierke's disease, which is a type of glycogen storage disease caused by a deficiency in the enzyme glucose-6-phosphatase, patients exhibit several characteristic metabolic abnormalities. One of the key findings is hyperlipidemia. This occurs because the inability to convert glycogen to glucose leads to an accumulation of glycogen and an increase in lipolysis, resulting in elevated levels of lipids in the bloodstream.

Patients may also present with hypoglycemia due to impaired gluconeogenesis and glycogenolysis, especially during fasting. The body's response to low glucose levels can further elevate lipid levels, as alternative energy pathways are activated, leading to increased fatty acid mobilization.

The other options do not accurately represent the typical findings seen in von Gierke's disease. For instance, hyperglycemia would not be observed due to the deficiency in glucose release from glycogen stores. Metabolic alkalosis is more commonly associated with different metabolic disorders, and an increased glucose response to epinephrine is not characteristic of this disease due to the impaired ability to utilize glucose in metabolic pathways.