What would be the expected PSA result 1 month after successful prostatectomy in a patient with initial PSA of 10.0 ng/mL?

After a successful prostatectomy, the prostate-specific antigen (PSA) levels in a patient should ideally drop to undetectable levels, particularly when the surgery is performed with curative intent and there is no residual prostate tissue. In men, PSA is primarily produced by prostate cells, so removal of the prostate gland typically results in a significant decline in PSA levels.

In most cases, one month following surgery, the expected result should be undetectable, indicating that the surgery has effectively eliminated the prostate source of the PSA. This is especially true if the initial PSA was 10.0 ng/mL, suggesting localized disease, which is often amenable to surgical intervention.

While other choices indicate various levels that may be seen in different circumstances, such as residual disease or benign prostatic tissue, these do not align with the anticipated outcome after complete and successful removal of the prostate during surgery. Thus, an undetectable PSA level is the hallmark response expected post-prostatectomy when no complications or incomplete procedures occur.