What will typically happen in metabolic alkalosis regarding potassium levels?

In metabolic alkalosis, the typical reaction regarding potassium levels is the development of hypokalemia, or low potassium levels. This occurs for several reasons related to the body’s attempt to maintain acid-base balance.

When the body experiences alkalosis, it often leads to an exchange reaction in renal physiology where hydrogen ions (H+) are moved from the intracellular to the extracellular space, and potassium ions (K+) shift in the opposite direction. This exchange results in a decrease in potassium levels in the bloodstream, contributing to hypokalemia.

Additionally, in response to metabolic alkalosis, the kidneys may increase the excretion of potassium as a compensatory mechanism. The kidneys aim to correct the alkalosis, and this process can result in further loss of potassium from the body.

In summary, metabolic alkalosis is closely associated with a decrease in serum potassium levels due to intracellular shift and renal adjustments, affirming that hypokalemia is the expected outcome.