What is the expected pH change in relation to body temperature above 37°C?

Study for the Harr Clinical Chemistry Test. Use flashcards and multiple choice questions for each topic covered. Each question includes hints and explanations to help you understand. Prepare effectively for success!

The expected pH change related to body temperature rising above 37°C is indeed a decrease in pH. As body temperature increases, the dissociation of carbonic acid in the blood is affected, leading to an increase in hydrogen ion concentration. This increase in hydrogen ions results in acidosis, which manifests as a decrease in pH.

Specifically, for every 1°C increase in body temperature, there is a general expectation of a pH decrease by approximately 0.015 units. Therefore, a temperature increase above the normal body temperature can lead to a measurable decrease in blood pH, shifting the acid-base balance toward a more acidic environment.

The relevance of this understanding lies in its applications in clinical settings, where changes in body temperature can occur due to various factors such as infections, inflammation, or hypermetabolic states. Monitoring these changes is crucial for managing patient care effectively.

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