What enzyme is likely elevated in muscle wasting disorders?

In muscle wasting disorders, the enzyme most likely to be elevated is aldolase. This enzyme plays a crucial role in glycolysis, helping to break down glucose for energy, which is particularly important in muscle tissue. When muscle is damaged or undergoing wasting, such as in conditions like muscular dystrophy or severe malnutrition, aldolase leaks into the bloodstream from the muscle cells, resulting in elevated serum levels.

Aldolase levels are often used as a biomarker to assess muscle injury and dysfunction, providing insight into the extent of muscle damage. Elevated levels indicate that there is an underlying muscle pathology, linking the enzyme specifically to muscle wasting conditions. The context of its function in muscle metabolism makes it the most relevant enzyme in this scenario.