In a patient’s biochemistry results, if the sodium level is significantly low while other levels are normal, what should be reported?

In the context of laboratory results, when a sodium level is significantly low while other biochemical markers remain normal, it's crucial to consider the integrity of the sample. A low sodium level could potentially be influenced by hemolysis or other pre-analytical factors.

By reporting the sodium results along with an estimate of the degree of hemolysis, the laboratory provides the clinician with valuable information regarding the quality of the sample. Hemolysis can cause spurious results, particularly in electrolytes such as sodium. If significant hemolysis is present, it could explain the falsely low sodium measurement. This transparency allows for a more accurate interpretation of the results and informs any further diagnostic decision-making by the healthcare provider.

In contrast, repeating a single test or requesting a new sample would not address the need to convey the potential impact of hemolysis on the sodium result. By reporting the sodium level alongside the hemolysis evaluation, the lab enables the healthcare team to make informed decisions based on a comprehensive understanding of the sample's quality and the reliability of the sodium measurement.